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Filtered Search Results
Apexbio Technology LLC 9-cis-Retinoic Acid 5300-03-8 25mg
9-cis-Retinoic Acid (CAS 5300-03-8) is a small-molecule agonist targeting retinoic acid receptors (RARs) and retinoid X receptors (RXRs) It is designed to activate these nuclear receptors thereby regulating transcription of genes involved in cell differentiation immune responses neural function proliferation and reproduction 9-cis-Retinoic Acid exerts its biological activity primarily through RAR/RXR-mediated gene regulation In in vitro studies 9-cis-Retinoic Acid modulates expression of myotrophin (Mptn) and miR-375 in pancreatic -cell and breast cancer cell lines It exhibits nanomolar binding affinity to RAR (Ki 0 5 27 nM) and RXR (Ki 3 8 12 nM) Based on these pharmacological properties 9-cis-Retinoic Acid holds research potential in oncology immunomodulation neuroprotection and dermatological conditions
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Medchemexpress LLC Maleimidoacetic acid N-hydroxysuccinimide ester | 55750-61-3 | MFCD00133523 | 99.6% | 252.18 g/mol | C10H8N2O6 | 250 MG
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AMAS (maleimidoacetic acid N-hydroxysuccinimide ester) is a noncleavable heterobifunctional crosslinker that carries an N-hydroxysuccinimide (NHS) ester and a maleimide group. It enables covalent conjugation between primary amines and free thiols to form stable amide and thioether bonds, and is used for bioconjugation and linker chemistry in antibody-drug conjugates and other crosslinking applications.
- Noncleavable heterobifunctional crosslinker with NHS ester and maleimide groups.
- Enables amine-to-thiol conjugation forming stable amide and thioether bonds.
- High purity suitable for sensitive bioconjugation workflows.
- Soluble in DMSO (about 100 mg/mL); ultrasonic assistance recommended.
- Store powder at -20°C; solutions require low-temperature storage.
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Medchemexpress LLC 1-Methyl-1-propylpip 5g
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1-Methyl-1-propylpiperidinium Bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research
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Medchemexpress LLC Lamotrigine | 84057-84-1 | MFCD00865333 | 99.99% | 250 MG
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Lamotrigine is the analytical standard of Lamotrigine, intended for research and analytical applications. It is a potent and orally active anticonvulsant or antiepileptic agent that selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. It can be used for the research of epilepsy, focal seizure, and other conditions.
- Selectively blocks voltage-gated Na+ channels
- Stabilizes presynaptic neuronal membranes
- Inhibits glutamate release
- Used in research for epilepsy and focal seizure
- Employed as a reference standard in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
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Medchemexpress LLC Tolbutamide | 64-77-7 | 99.96% | 250 MG
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Tolbutamide is an orally active KATP inhibitor used in diabetes research. It inhibits cell proliferation, stimulates the exocytosis of glucagon, and has been observed to reduce fetal lethality in mice. This compound is suitable for various in vitro and in vivo studies.
- Orally active KATP inhibitor
- Inhibits cell proliferation
- Stimulates exocytosis of glucagon
- Reduces fetal lethality in mice
- Used in diabetes research
- Reduces glioma cell proliferation
- Activates mitochondrial-like KATP channels
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Medchemexpress LLC Cefadroxil | 50370-12-2 | 99.54% | 250 MG
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Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. It inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Its small intestinal absorption is dependent on the intestinal peptide transporter PepT1. Cefadroxil exhibits inhibitory and bactericidal activity against various Gram-positive and Gram-negative bacteria and also possesses analgesic effects on neuropathic pain.
- Inhibits bacterial cell wall synthesis
- Enhances glutamate transporter-1 expression
- Active against Gram-positive and Gram-negative bacteria
- Exhibits analgesic effects on neuropathic pain
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Medchemexpress LLC Ethyl 3-aminopropionate hydrochloride | 4244-84-2 | MFCD00012909 | ≥98.0% | 153.61 | C5H12ClNO2 | 500g
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Ethyl 3-aminopropionate hydrochloride is an alanine derivative[1]
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Medchemexpress LLC DL-3-phenyllactic acid | 828-01-3 | MFCD00065928 | 99.9% | 166.17 g/mol | C9H10O3 | 10 MG
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DL-3-phenyllactic acid is a racemic analytical standard used as an endogenous metabolite reference in research and method development. It is a small organic acid (C9H10O3, CAS 828-01-3) with a molecular weight of about 166.17 g/mol, supplied as a high-purity solid for analytical applications.
- High purity for use as an analytical standard and calibration reference.
- Suitable for chromatography and mass spectrometry method development.
- Small solid quantity packaging for reference and trace-level analyses.
- Well-characterized chemical identifiers aid database matching and reporting.
- Stable under recommended storage for consistent analytical results.
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Medchemexpress LLC 2-oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl] | 88321-09-9 | MFCD00132883 | 99.6% | 342.43 g/mol | C17H30N2O5 | 250 MG
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Aloxistatin (E64d) is a cell-permeable, irreversible, broad-spectrum cysteine protease inhibitor used in research to block cathepsin activity and disrupt protease-dependent processes, including viral entry and protein processing. It has reported antiviral and in vivo biological effects and is supplied with supporting solubility and storage guidance in the manufacturer datasheet.
- Cell-permeable, irreversible inhibitor of cysteine proteases.
- Broad-spectrum activity against cathepsins and related proteases.
- Reported entry-blocking effect for MERS-CoV.
- Inhibits protease-resistant prion protein accumulation (IC50 ~0.5 μM).
- Soluble in DMSO and ethanol; formulation guidance provided for in vivo use.
- Powder stable at low temperatures; solvent aliquots recommended for long-term storage.
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eMolecules 1227948-82-4 | Ifebemtinib | Ambeed588.564 | C28H28F4N6O4 | 99.000 | COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(c(Oc2cccc3CN(C)C(=O)c23)n1)C(F)(F)F | 250mg | 879141650
Ifebemtinib | Ambeed | 1227948-82-4588.564 | C28H28F4N6O4 | 99.000 | COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(c(Oc2cccc3CN(C)C(=O)c23)n1)C(F)(F)F | 250mg | 879141650
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Medchemexpress LLC Thioacetanilide (N-Phenylthioacetamide) | 637-53-6 | 98.4% | 250 MG
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Thioacetanilide (N-Phenylthioacetamide) | 637-53-6 | 98.4% | 250 MG
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Medchemexpress LLC 2'-O-MOE-5MeU-3'-phosphoramidite | 163878-63-5 | MFCD11505865 | ≥97.0% | 818.89 | C43H55N4O10P | 250 MG
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2'-O-MOE-5MeU-3'-phosphoramidite is a phosphoramidite monomer used to incorporate 2'-O-methoxyethyl-modified 5-methyluridine into oligonucleotides by automated solid-phase synthesis. It is supplied as a white to off-white solid (molecular weight 818.89; formula C43H55N4O10P) with a typical purity of ≥97% and is offered in multiple pack sizes for research use.
- Compatible with automated solid-phase oligonucleotide synthesis.
- Enables incorporation of 2'-O-methoxyethyl-modified 5-methyluridine residues.
- Supplied as a white to off-white solid with documented molecular weight and formula.
- Typical purity ≥97% suitable for research applications.
- Available in multiple pack sizes to support different synthesis scales.
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Medchemexpress LLC N-Ethyl-N-nitrosoure | 759-73-9 | 10g
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N-Ethyl-N-nitrosourea (ENU) is a DNA alkylating agent N-Ethyl-N-nitrosourea induces leukemia by alkylating nucleobases disrupting DNA and resulting in bone marrow suppression and the formation of leukemic cells N-Ethyl-N-nitrosourea is teratogenic in vivo inducing tumor formation and paw malformations in pregnant rats N-Ethyl-N-nitrosourea cause central nervous system (CNS) tumors and genetic disorders[1][2]
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eMolecules 51359-78-5 | 4-Bromomethylbenzaldehyde | ChemScene | MFCD08271963 | 199.047 | C8H7BrO | 97.000 | BrCc1ccc(C=O)cc1 | 250mg | 665615583
4-Bromomethylbenzaldehyde | ChemScene | 51359-78-5 | MFCD08271963 | 199.047 | C8H7BrO | 97.000 | BrCc1ccc(C=O)cc1 | 250mg | 665615583
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eMolecules 287714-35-6 | Methyl 2-chloropyrimidine-5-carboxylate | Ambeed | MFCD08690330 | 172.570 | C6H5ClN2O2 | 98.000 | COC(=O)c1cnc(Cl)nc1 | 1g | 490524353
Methyl 2-chloropyrimidine-5-carboxylate | Ambeed | 287714-35-6 | MFCD08690330 | 172.570 | C6H5ClN2O2 | 98.000 | COC(=O)c1cnc(Cl)nc1 | 1g | 490524353
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